Could you live in a tiny living space?

I posted about living off-grid and I'm curious what people think about living in a tiny house or a small space. 

Could you live in a tiny house or a space that's less than 500 square feet? 

The site Treehugger has a lot of information about "Tiny Houses." I could live in a tiny house if I had access to land to garden or access to nature. 

Treehugger listed the "Top 10 tiny homes of the decade." 

I'm living in a northern climate and could see myself living in this space.